Meaning in life reflects the feeling that one’s existence has significance, purpose, and coherence (see Heintzelman and King, 2014). A growing body of research identifies meaning in life as a fundamental human need that strongly influences both psychological and physical well-being (see Vail and Routledge, 2020). Individuals who perceive their lives as full of meaning live longer, healthier, and happier lives than those less inclined to view their lives as meaningful. Despite the growing recognition that meaning in life is vital for humans, scholars have largely ignored how meaning influences broader societal flourishing. We propose that meaning has important social and economic implications, particularly when societies are facing major existential threats such as the current COVID-19 pandemic. More specifically, we argue that meaning functions as a self-regulatory and motivational intrapsychic resource that orients people toward the types of cognitions and behaviors that build and sustain healthy communities and societies.